Map genetic diversity
Characterize genetic variation across Senegal’s ethnolinguistic communities and establish a representative reference sequence.
Together for Genomic medicine in Senegal
SEN-GENOME is an innovative research project led by Cheikh Anta Diop University (UCAD) that aims to explore the genetic diversity of Senegalese populations. Its objective is to establish a national reference genomic resource to enhance our understanding of the history of human settlement in Senegal and support the development of personalized medicine. By analyzing genetic data from participants representing the country’s diverse ethnolinguistic communities, the project helps strengthen the representation of African populations in global genomic research. SEN-GENOME ultimately seeks to advance scientific innovation, improve disease prevention, and enhance healthcare delivery in Senegal.
Led by Senegalese researchers
National scope
Ethical & inclusive
IN PARTNERSHIP WITH
1015Participants selected
31Ethnolinguistic groups
5,000+Biological samples stored
334Whole Genome Sequence 10X
1National reference genome
Why SEN-GENOME matters
Closing the genomic data gap
African populations remain severely underrepresented in global genomic databases despite having the greatest genetic diversity. SEN-GENOME addresses this imbalance by generating locally relevant knowledge and building infrastructure in Senegal.
Our mission
Three pillars for long-term impact
From discovery to clinical application, the project connects science, capacity building and public health.
Build national capacity
Develop biobanking, human genomics and bioinformatics capabilities while training researchers, clinicians and specialists.
Improve public health
Identify genetic factors linked to priority diseases and support the development of locally relevant diagnostic and prevention tools.
Project progress
From recruitment to reference genome
Completed
Participant recruitment
1,015 participants recruited across all 14 administrative regions, covering 31 identified ethnolinguistic groups.
Completed
Biobank and DNA extraction
Sociodemographic, anthropometric and biological data were securely collected, with DNA extracted for all recruited participants.
In progress
Sequencing and genomic analysis
334 participants were selected for low-coverage whole-genome sequencing.
Next milestone
Senegalese reference genome
Long-read, high-coverage sequencing of representative samples will support construction of the national reference genome.
Future impact
Precision medicine adapted to the population
SEN-GENOME can help Senegal improve care for infectious diseases, inherited conditions, cancers and chronic diseases while becoming a regional centre of excellence.
Support the next phase01Better diagnostic biomarkers
02More relevant treatment strategies
03Protected national genomic data
04New training and research pathways
A national ambition
Meet the team
“Towards a Senegal that leads genomic medicine in Francophone West Africa.”